E222

What is E222?

Sodium bisulphite (sodium hydrogen sulphite) — a sulphite preservative and antioxidant in the E220–E228 group, used in dried fruit, wine and other foods, with the same declaration rules and hypersensitivity notes as other sulphites.

Quick answer

Sodium bisulphite (E222), also called sodium hydrogen sulphite or sodium bisulfite, is a sulphite used as a preservative and antioxidant (for example to limit browning) in dried fruit, wine, potato products and other foods. It is assessed with the wider sulphite group (E220–E228). It is permitted in Australia/NZ, the EU and the US within set limits, and must usually be declared when present at 10 milligrams per kilogram or more. EFSA's 2022 follow-up withdrew the temporary group Acceptable Daily Intake for sulphur dioxide–sulphites because toxicity data remained inadequate, and instead used a margin-of-exposure approach that raised a safety concern for high consumers in most population groups. Regulators and allergy bodies have long noted that sulphites may be associated with asthma-like symptoms in some sensitive individuals. Goodnessly rates it Avoid.

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Read the FAQ →

What is sodium bisulphite?

Sodium bisulphite (E222) is the sodium salt of bisulphurous acid (also labelled sodium hydrogen sulphite). It is an inorganic sulphite preservative and antioxidant. It belongs to the wider sulphite group that also includes sulphur dioxide (220), sodium sulphite (221), sodium metabisulphite (223), potassium metabisulphite (224) and related salts (226–228). Sulphites can also occur naturally in some foods; the additive form is added deliberately for preservation or anti-browning. On labels you may see "sodium bisulphite", "sodium bisulfite" (US spelling), "sodium hydrogen sulphite", "222", or the class name "preservative" / "antioxidant" with the number.

What's it used for?

  • Preserving dried fruit and limiting browning in dried fruit and vegetables
  • Used in wine, beer and other fermented drinks as part of sulphite management
  • Limiting spoilage and browning in some potato products and processed vegetables
  • Used in selected fruit juices, cordials and other permitted processed foods

Where you'll find E222 on the shelf

Like other sulphites, it turns up in dried fruit, wine and some processed foods — always check the ingredients list if you are sulphite-sensitive.

Dried fruit & dried vegetables
Wine, beer & cider
Potato products
Fruit juices & cordials
Some processed vegetables
Selected condiments

Is sodium bisulphite safe? What the research says

Sodium bisulphite is regulated as part of the sulphur dioxide–sulphites group. Major markets still permit it within limits and require declaration at or above 10 mg/kg, while EFSA's latest group assessment withdrew the temporary ADI and flagged a safety concern for high consumers. Sulphites have long been associated in clinical and regulatory literature with adverse reactions in some people with asthma — an association that is still incompletely quantified.

Region Status What this means
AU/NZ Australia & New Zealand (FSANZ) Permitted; declare ≥10 mg/kg Permitted under the Food Standards Code for specified foods at maximum levels (often expressed as sulphur dioxide equivalents). Added sulphites must be declared when present at 10 milligrams per kilogram (10 mg/kg) or more. FSANZ and Australian allergy guidance note that sulphite sensitivity is more common among people with asthma.
EU European Union (EFSA) Permitted; ADI withdrawn 2022 Authorised as E222 (sodium hydrogen sulphite / sodium bisulphite) within the E220–E228 group. EFSA's 2016 re-evaluation set a temporary group ADI of 0.7 milligrams of SO₂ equivalents per kilogram of body weight per day. The 2022 follow-up withdrew that temporary ADI because the toxicity database remained inadequate, applied a margin-of-exposure approach (reference point 38 mg SO₂ equivalents/kg bw/day; assessment factor 80), and concluded this raises a safety concern for estimated dietary exposures in both refined and maximum-permitted-level scenarios for most population groups. EFSA also restated the need to further investigate hypersensitivity among some sensitive consumers.
US United States (FDA) GRAS; declare ≥10 ppm Sodium bisulfite is listed as generally recognized as safe under 21 CFR 182.3739 when used in accordance with good manufacturing practice, with carve-outs including meats, foods recognised as a source of vitamin B1, and fruits or vegetables intended to be served or sold raw/fresh. Sulfiting agents must generally be declared when present at 10 parts per million (10 mg/kg) or more; functional sulfites must be declared regardless of level.

Wording matters here: regulators describe sulphite-related breathing difficulties in some sensitive people — particularly some people with asthma — as a recognised hypersensitivity concern, not as proof that sodium bisulphite will cause asthma in the general population. Prevalence estimates vary; ASCIA and similar bodies advise sulphite-sensitive individuals to read labels carefully.

📰 Recent developments Last checked September 2026
  • EFSA 2022 follow-up (group E220–E228): withdrew the temporary group ADI; used a margin-of-exposure approach and concluded estimated intakes raise a safety concern for high consumers in all population groups except adolescents (refined scenario). Sodium bisulphite (E222) is included in that group assessment.
  • Hypersensitivity data gaps: EFSA restated its recommendation to further investigate hypersensitivity or intolerance among some sensitive consumers, because knowledge gaps remain.
  • Label thresholds unchanged: AU/NZ and US still generally require sulphite declaration at or above 10 mg/kg (10 ppm), so the practical shopping cue on dried fruit and wine labels remains the same.

This section is checked periodically rather than continuously — if you're reading this well after the date above, it's worth confirming nothing has changed before citing it.

Who might want to limit or avoid it

  • People with asthma or a known sulphite sensitivity, given longstanding clinical and regulatory notes that sulphites may be associated with wheezing or other reactions in some sensitive individuals
  • High consumers of dried fruit, wine or other sulphited foods, given EFSA's 2022 finding that estimated intakes raise a safety concern for high consumers in most age groups
  • Anyone who prefers to minimise preservative sulphites and can choose unsulphited dried fruit or lower-sulphite wine options where available

Goodnessly rates E222 Avoid. Sodium bisulphite remains permitted within set limits in Australia/NZ, the EU and the US, but EFSA's 2022 withdrawal of the temporary group ADI for E220–E228, the margin-of-exposure concern for high consumers, and the well-recognised association between sulphites and adverse reactions in some sensitive people — including some people with asthma — place it in our highest-caution category.

How to spot it on a label

E222 and related sulphites must usually be declared when at or above 10 mg/kg. Look out for:

  • Sodium bisulphite / sodium bisulfite / sodium hydrogen sulphite
  • 222 or E222
  • Preservative (222) or antioxidant (222)
  • Other sulphites: 220, 221, 223–228 (sulphur dioxide and related sulphite salts)

Especially common alongside other sulphites on dried fruit, wine and some potato-product labels.

Frequently asked questions

What is Sodium bisulphite (E222) made from?

Sodium bisulphite is an inorganic salt (also called sodium hydrogen sulphite) manufactured for use as a food preservative and antioxidant. In food it belongs to the sulphite group (E220–E228). Small amounts of sulphites can also occur naturally in some foods.

Is sodium bisulphite the same as sodium metabisulphite?

They are related but not identical. Sodium bisulphite is E222; sodium metabisulphite is E223. Both are assessed together in the EFSA sulphite group (E220–E228), and residual sulphite on labels is often expressed as sulphur dioxide equivalents. Check the number or full name on the ingredients list.

Can sodium bisulphite affect people with asthma?

Sulphites have long been associated in clinical and regulatory literature with adverse reactions — including asthma-like symptoms such as wheezing — in some sensitive individuals, and sensitivity appears more common among people who already have asthma. That is an association for a sensitive subgroup, not evidence that sodium bisulphite causes asthma in the general population. If you have asthma or a known sulphite sensitivity, check labels and follow clinical advice.

Does Goodnessly rate E222 as safe, caution or avoid?

Goodnessly rates E222 (Sodium bisulphite) as Avoid. It remains permitted within set limits, but EFSA's 2022 group ADI withdrawal and high-consumer concern, plus the recognised association with reactions in some sulphite-sensitive people, place it in our highest-caution category.

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