L-Glutamic acid — the parent amino acid of the E620–E625 glutamate flavour-enhancer group (MSG and related salts).
L-Glutamic acid (E620) is a flavour enhancer and the parent acid of the glutamate salts monosodium glutamate (E621), monopotassium glutamate (E622), calcium glutamate (E623), monoammonium glutamate (E624) and magnesium glutamate (E625). It contributes the savoury "umami" taste used in seasonings, soups, sauces and many processed savoury foods. It is permitted in Australia/NZ and the EU within the glutamates group. EFSA's 2017 re-evaluation set a group ADI of 30 mg/kg body weight per day (expressed as glutamic acid) and noted that estimated exposures for some high consumers could exceed that ADI. In the US, glutamic acid is listed as GRAS under 21 CFR 182.1045 (salt substitute under GMP); MSG itself is long-standing GRAS. Goodnessly rates it Avoid.
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Read the FAQ →L-Glutamic acid is an amino acid that occurs naturally in many protein-rich foods. As a food additive (E620) it is manufactured for use as a flavour enhancer, often alongside or instead of its sodium salt MSG (E621). Regulators assess E620–E625 as one group. On labels you may see "L-glutamic acid", "glutamic acid", "620", "E620", or "flavour enhancer (620)".
Same neighbourhood as MSG — savoury processed foods. The free acid is less common on everyday labels than monosodium glutamate (621), but the group shares one EFSA ADI.
Glutamates are among the most debated flavour enhancers. EFSA keeps a numerical group ADI and has flagged that high consumers of additive glutamates may exceed it, recommending review of some EU maximum levels. FDA continues to treat glutamic acid / MSG uses as GRAS. Reports of sensitivity in a subgroup of people after high-glutamate meals are discussed in the literature as associations for susceptible individuals — not proof that glutamic acid "causes" a defined disease in the general population.
| Region | Status | What this means |
|---|---|---|
| AU/NZ Australia & New Zealand (FSANZ) | Permitted (glutamates group, GMP) | Listed with other glutamates (620–625) in the Food Standards Code as flavour enhancers, generally at GMP for permitted categories. Must be declared by name or code number when used as a food additive (for example flavour enhancer (620)). |
| EU European Union (EFSA) | Authorised; group ADI 30 mg/kg bw/day | Authorised as E620 under Regulation (EC) No 1333/2008. EFSA's 2017 re-evaluation of E620–E625 set a group ADI of 30 mg/kg bw/day expressed as glutamic acid, and noted that exposure estimates for some population groups could exceed the ADI and doses associated with adverse effects in humans, recommending review of MPLs in several categories. |
| US United States (FDA) | GRAS (21 CFR 182.1045) | Glutamic acid is listed as GRAS under 21 CFR 182.1045 when used as a salt substitute under good manufacturing practice. Monosodium glutamate is separately recognised as GRAS in longstanding FDA materials. Federal listings remain in force as of this draft (September 2026). |
Naturally occurring glutamate in tomatoes, cheese or mushrooms is not the same regulatory listing as additive E620, but chemistry overlaps — this page is about the intentionally added additive. Sensitivity reports after high-glutamate meals describe associations in susceptible people; they are not a general-population diagnosis.
This section is checked periodically rather than continuously — if you're reading this well after the date above, it's worth confirming nothing has changed before citing it.
Goodnessly rates E620 Avoid. L-glutamic acid remains permitted in Australia/NZ and the EU within the glutamates group, and is GRAS in the US, but EFSA's group ADI exposure concerns for high consumers and our preference to skip deliberate umami boosters place it with MSG in Avoid.
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MSG (621) is the salt you will see most often — same EFSA group ADI.
It is an amino acid manufactured for use as a flavour enhancer. It is the parent acid of the glutamate salts E621–E625 (including MSG). Commercial production is typically by fermentation.
They are in the same group. MSG is the monosodium salt (E621). Regulators assess E620–E625 together with a shared group ADI in the EU. Goodnessly rates the whole group Avoid.
No. EFSA set a group ADI of 30 mg/kg bw/day and recommended reviewing some maximum levels because high-consumer exposure estimates could exceed the ADI. That is not a ban.
Goodnessly rates E620 (L-glutamic acid) as Avoid, consistent with other glutamates in our ratings.
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